Hederasaponin C ameliorates chronic obstructive pulmonary disease pathogenesis by targeting TLR4 to inhibit NF-κB/MAPK signaling pathways

Hederasaponin C ameliorates chronic obstructive pulmonary disease pathogenesis by targeting TLR4 to inhibit NF-κB/MAPK signaling pathways

Abstract Background Chronic obstructive pulmonary disease (COPD) is a complex respiratory disorder characterized by persistent respiratory symptoms and progressive airflow limitation. Long-term exposure to harmful particulates and gases causes structural abnormalities in the airways and alveoli, act...

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Bibliographic Details
Main Authors: Yujie Ning, Liting Huang, Qin-Qin Wang, Lina Liu, Xinghua Ni, Xiaoyun Xie, Jingyu Liu, Qian Su, Shilin Yang, Renyikun Yuan, Hongwei Gao
Format: Article
Language:English
Published: BMC 2025-07-01
Series:Chinese Medicine
Subjects:
Hederasaponin C
COPD
TLR4
Inflammation
Online Access:https://doi.org/10.1186/s13020-025-01155-5
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