Glial fibrillary acidic protein in plasma and intraocular fluids and the correlation with cognitive function in patients with vitreoretinal disease

Glial fibrillary acidic protein in plasma and intraocular fluids and the correlation with cognitive function in patients with vitreoretinal disease

Abstract Ocular imaging and fluid protein levels are emerging as biomarkers for neurodegenerative disease. Elevated levels of plasma glial fibrillary acidic protein (GFAP), a marker of astrogliosis, have been demonstrated early in the course of Alzheimer’s Disease. In this study, we measured GFAP le...

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Main Authors: Steven Ness, Konstantina Sampani, Fatima Tuz-Zahra, Nurgul Aytan, Sreevardhan Alluri, Marissa G. Fiorello, Xuejing Chen, Nicole H. Siegel, Michael L. Alosco, Weiming Xia, Yorghos Tripodis, Thor D. Stein, Manju L. Subramanian
Format: Article
Language:English
Published: Nature Portfolio 2025-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-025-13260-4
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https://doi.org/10.1038/s41598-025-13260-4

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