Decidual/placental and first trimester plasma levels of hsa-miR-199a-3p|hsa-miR-199b-3p and hsa-miR-3150b-3p are associated with insulin secretion in pregnancy

Decidual/placental and first trimester plasma levels of hsa-miR-199a-3p|hsa-miR-199b-3p and hsa-miR-3150b-3p are associated with insulin secretion in pregnancy

Background/AimsThe placenta expresses and releases specific microRNAs (miRNAs) into the maternal circulation that may influence insulin secretion during pregnancy. We hypothesized that specific decidual/placental miRNAs are associated with maternal insulin secretion during pregnancy.MethodsIn the Ge...

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Main Authors: Amélie Taschereau, Frédérique White, Catherine Allard, Andrea G. Edlow, François Aguet, Kristin G. Ardlie, Jose C. Florez, Pierre-Étienne Jacques, S. Ananth Karumanchi, Camille E. Powe, Luigi Bouchard, Marie-France Hivert
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-08-01
Series:Frontiers in Endocrinology
Subjects:
pregnancy
placenta
insulin secretion
diabetes
microRNA
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2025.1622500/full
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https://www.frontiersin.org/articles/10.3389/fendo.2025.1622500/full

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