The emerging role of vascular endothelial cell-mediated angiogenesis in the imbalance of RA synovial microenvironment and its clinical relevance

The emerging role of vascular endothelial cell-mediated angiogenesis in the imbalance of RA synovial microenvironment and its clinical relevance

Vascular endothelial cells (VEC) play a key role in the occurrence and progression of vascular inflammation. VEC activation secretes powerful inflammatory mediators and aggravates the development of rheumatoid arthritis (RA). Angiogenesis plays a key role in the pathological processes of inflammatio...

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Bibliographic Details
Main Authors: Xingxing Huo, Yanhui Peng, Hui Li, Chen Li, Faxue Liao, Chenggui Miao, Yurong Huang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-04-01
Series:Frontiers in Pharmacology
Subjects:
rheumatoid arthritis
vascular endothelial cells
angiogenesis
fibroblastoid synovial cells
macrophages
post-translational modification
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2025.1481089/full
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https://www.frontiersin.org/articles/10.3389/fphar.2025.1481089/full

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