Deep learning and genome-wide association meta-analyses of bone marrow adiposity in the UK Biobank

Deep learning and genome-wide association meta-analyses of bone marrow adiposity in the UK Biobank

Abstract Bone marrow adipose tissue is a distinct adipose subtype comprising more than 10% of fat mass in healthy humans. However, the functions and pathophysiological correlates of this tissue are unclear, and its genetic determinants remain unknown. Here, we use deep learning to measure bone marro...

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Main Authors: Wei Xu, Ines Mesa-Eguiagaray, David M. Morris, Chengjia Wang, Calum D. Gray, Samuel Sjöström, Giorgos Papanastasiou, Sammy Badr, Julien Paccou, Xue Li, Paul R. H. J. Timmers, Maria Timofeeva, Susan M. Farrington, Malcolm G. Dunlop, Scott I. Semple, Tom MacGillivray, Evropi Theodoratou, William P. Cawthorn
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-55422-4
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https://doi.org/10.1038/s41467-024-55422-4

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