Hsa_circ_0020491 promotes polycystic ovary syndrome by interacting with IGF2BP2 through regulation of granular cell autophagy and mitochondrial dysfunction

Hsa_circ_0020491 promotes polycystic ovary syndrome by interacting with IGF2BP2 through regulation of granular cell autophagy and mitochondrial dysfunction

Polycystic ovary syndrome (PCOS) is a prevalent endocrine disorder in women, yet its underlying mechanisms remain incompletely understood. This study investigated the role of hsa_circ_0020491 in PCOS pathogenesis, focusing on granulosa cells (GCs). Analysis of GCs from PCOS patients and controls rev...

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Bibliographic Details
Main Authors: XiaLing Huang, Fen Yu
Format: Article
Language:English
Published: Taylor & Francis Group 2025-12-01
Series:Gynecological Endocrinology
Subjects:
Polycystic ovary syndrome
hsa_circ_0020491
IGF2BP2
granular cells
autophagy
mitochondria
Online Access:https://www.tandfonline.com/doi/10.1080/09513590.2025.2536579
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https://www.tandfonline.com/doi/10.1080/09513590.2025.2536579

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