A Bayesian method to incorporate hundreds of functional characteristics with association evidence to improve variant prioritization.

The increasing quantity and quality of functional genomic information motivate the assessment and integration of these data with association data, including data originating from genome-wide association studies (GWAS). We used previously described GWAS signals ("hits") to train a regulariz...

Full description

Saved in:
Bibliographic Details
Main Authors: Sarah A Gagliano, Michael R Barnes, Michael E Weale, Jo Knight
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0098122
Tags: Add Tag
No Tags, Be the first to tag this record!