Interplay of PAK1 and CAMKII in Pancreatic Beta Cell Insulin Secretion

Interplay of PAK1 and CAMKII in Pancreatic Beta Cell Insulin Secretion

Background/Objectives: Type 2 diabetes mellitus (T2DM) is a major global health challenge, primarily driven by insulin resistance and beta-cell dysfunction. This study investigated the roles of p21-activated kinase 1 (PAK1) and calcium/calmodulin-dependent protein kinase II (CAMKII) in insulin secre...

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Main Authors: Nely Gisela López-Desiderio, Genaro Patiño-López, Citlaltépetl Salinas-Lara, Carlos Sánchez-Garibay, Olga Villamar-Cruz, Alonso Vilches-Flores, José de Jesús Peralta-Romero, Leonel Armas-López, Jazmín García-Machorro, Luis Enrique Arias-Romero, Héctor Iván Saldívar-Cerón
Format: Article
Language:English
Published: MDPI AG 2025-05-01
Series:Diabetology
Subjects:
Type 2 diabetes
insulin secretion
PAK1
CAMKII
kinase inhibitors
bioinformatics
Online Access:https://www.mdpi.com/2673-4540/6/5/39
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https://www.mdpi.com/2673-4540/6/5/39

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