Bilosomes and Niosomes for Enhanced Intestinal Absorption and In Vivo Efficacy of Cytarabine in Treatment of Acute Myeloid Leukemia

Bilosomes and Niosomes for Enhanced Intestinal Absorption and In Vivo Efficacy of Cytarabine in Treatment of Acute Myeloid Leukemia

Cytarabine (CTR) is a hydrophilic anticancer drug used to treat leukemia. It suffers from poor permeability and intestinal metabolism, diminishing its oral bioavailability. Background/Objectives: The objective was to develop and evaluate niosomes and bilosomes for enhanced intestinal absorption; hen...

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Bibliographic Details
Main Authors: Abdelrahman R. Said, Mona F. Arafa, Walaa A. El-Dakroury, Sultan Alshehri, Gamal M. El Maghraby
Format: Article
Language:English
Published: MDPI AG 2024-11-01
Series:Pharmaceuticals
Subjects:
bilosomes
niosomes
intestinal perfusion
leukemia
cytarabine
Online Access:https://www.mdpi.com/1424-8247/17/12/1572
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