CTSS in the tumor microenvironment links immune escape and immunotherapy sensitivity in kidney renal clear cell carcinoma

CTSS in the tumor microenvironment links immune escape and immunotherapy sensitivity in kidney renal clear cell carcinoma

Abstract The tumor microenvironment (TME) of kidney renal clear cell carcinoma (KIRC) exhibits complex dynamics among immune, stromal, and malignant cells that drive immune escape (IE) mechanisms and influence clinical outcomes. Through single-cell RNA sequencing and high-dimensional weighted gene c...

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Bibliographic Details
Main Authors: Hanjing Zhou, Jun Ying, Xuchun Xu, Jian Huang
Format: Article
Language:English
Published: Springer 2025-07-01
Series:Discover Oncology
Subjects:
KIRC
CTSS
Immune escape
Machine learning
Immunotherapy
Online Access:https://doi.org/10.1007/s12672-025-03267-8
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https://doi.org/10.1007/s12672-025-03267-8

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