Ginsenoside Rg1 alleviates ochratoxin A-induced liver inflammation in ducklings: Involvement of intestinal microbiota modulation and the TLR4/NF-κB pathway inhibition

Ginsenoside Rg1 alleviates ochratoxin A-induced liver inflammation in ducklings: Involvement of intestinal microbiota modulation and the TLR4/NF-κB pathway inhibition

Ochratoxin A (OTA) is a toxic fungal secondary metabolite that triggers liver inflammation in animals. OTA could disrupt intestinal microbiota balance by promoting Gram-negative bacteria growth and activating the Toll-like receptor 4 (TLR4)/Nuclear factor-kappa B (NF-κB) signaling pathway, thereby i...

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Bibliographic Details
Main Authors: Shuangshuang Zhai, Xin Peng, Cheng Liu, Ran Zhang, Chunlong Jin, Xiayu Jiang, Peishi Feng, Yuting Liang, Xi Yuan, Jinqiu Zhang, Ye Yang
Format: Article
Language:English
Published: Elsevier 2025-05-01
Series:Ecotoxicology and Environmental Safety
Subjects:
Ginsenoside Rg1
Ochratoxin A
Intestinal microbiota
TLR4/NF-κB signaling pathway
Liver inflammation
Online Access:http://www.sciencedirect.com/science/article/pii/S0147651325005226
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