The Role of Protein Ubiquitination in the Onset and Progression of Sepsis

The Role of Protein Ubiquitination in the Onset and Progression of Sepsis

Sepsis is a life-threatening condition characterized by a dysregulated host response to infection, with complex pathophysiological mechanisms. As an important post-translational modification, protein ubiquitination exhibits multiple non-traditional functions in sepsis beyond its conventional role in...

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Bibliographic Details
Main Authors: Meng-Yan Chen, Yang Liu, Min Fang
Format: Article
Language:English
Published: MDPI AG 2025-07-01
Series:Cells
Subjects:
ubiquitination
sepsis
NF-κB
NLRP3 inflammasome
septic organ injury
macrophage polarization
Online Access:https://www.mdpi.com/2073-4409/14/13/1012
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