Insulin and Metformin are Associated With Reduced Risk of Amyotrophic Lateral Sclerosis

Abstract Background Type 2 diabetes (T2D), but not type 1, protected against amyotrophic lateral sclerosis (ALS). In T2D serum insulin is normal or elevated in the early stages. Type 1 diabetes, characterized by a total lack of insulin, is associated with an increased risk of ALS. The antidiabetic m...

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Bibliographic Details
Main Authors: Steven Lehrer, Peter H. Rheinstein
Format: Article
Language:English
Published: Wiley 2025-06-01
Series:Chronic Diseases and Translational Medicine
Subjects:
Online Access:https://doi.org/10.1002/cdt3.141
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