Adipocyte Septin-7 attenuates obesogenic adipogenesis and promotes lipolysis to prevent obesity

Adipocyte Septin-7 attenuates obesogenic adipogenesis and promotes lipolysis to prevent obesity

Objectives: The white adipose tissue (WAT) expansion plays a significant role in the development of obesity. Cytoskeletal remodeling directly impacts adipogenic program, however, the precise mechanism remains poorly understood. Here, we identified a crucial role of Septin-7 (SEPT7), a cytoskeleton c...

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Main Authors: Liran Xu, Chao Yang, Kaidan Pang, Ying Zhang, Yu He, Siyu Liu, Huijing Tian, Zehua Shao, Siyu Wang, Xingqian Liu, Ting Li, Yapeng Cao, Luqin Yan, Jinjin Liu, Yanan Wang, Yongxin Li, Wei Zhao, Youhua Wang, Yang Yan, Shengpeng Wang
Format: Article
Language:English
Published: Elsevier 2025-05-01
Series:Molecular Metabolism
Subjects:
Septin-7
Obesity
Adipocyte
Adipogenesis
Online Access:http://www.sciencedirect.com/science/article/pii/S2212877825000213
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