Sesquiterpene lactones downregulate G2/M cell cycle regulator proteins and affect the invasive potential of human soft tissue sarcoma cells.

Sesquiterpene lactones downregulate G2/M cell cycle regulator proteins and affect the invasive potential of human soft tissue sarcoma cells.

Soft tissue sarcomas (STS) represent a rare group of malignant tumors that frequently exhibit chemotherapeutic resistance and increased metastatic potential. Many studies have demonstrated the great potential of plant-derived agents in the treatment of various malignant entities. The present study i...

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Main Authors: Birgit Lohberger, Beate Rinner, Nicole Stuendl, Heike Kaltenegger, Bibiane Steinecker-Frohnwieser, Eva Bernhart, Ehsan Bonyadi Rad, Annelie Martina Weinberg, Andreas Leithner, Rudolf Bauer, Nadine Kretschmer
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0066300&type=printable
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https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0066300&type=printable

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