Influenza H5Nx viruses are susceptible to MEK1/2 inhibition by zapnometinib

Influenza H5Nx viruses are susceptible to MEK1/2 inhibition by zapnometinib

Highly pathogenic avian influenza A viruses (HPAIV) pose a significant threat to both animal and human health. These viruses have the potential to cause severe respiratory and systemic infections in birds and several mammalian species. The recent global outbreak of the H5N1 clade 2.3.4.4b spread in...

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Bibliographic Details
Main Authors: André Schreiber, Nicole Oberberg, Benjamin Ambrosy, Franziska Rodner, Sriram Kumar, Duygu Merve Caliskan, Linda Brunotte, Martin Beer, Stephan Ludwig
Format: Article
Language:English
Published: Taylor & Francis Group 2025-12-01
Series:Emerging Microbes and Infections
Subjects:
HPAIV
antiviral drug treatment
Raf/MEK/ERK signalling pathway
MEK1/2 inhibition
Zapnometinib
Online Access:https://www.tandfonline.com/doi/10.1080/22221751.2025.2471022
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https://www.tandfonline.com/doi/10.1080/22221751.2025.2471022

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