Identification and validation of m6A RNA methylation and ferroptosis-related biomarkers in sepsis: transcriptome combined with single-cell RNA sequencing

Identification and validation of m6A RNA methylation and ferroptosis-related biomarkers in sepsis: transcriptome combined with single-cell RNA sequencing

BackgroundSepsis, a systemic inflammatory response syndrome triggered by infection, is associated with high mortality rates and an increasing global incidence. While N6-methyladenosine (m6A) RNA methylation and ferroptosis are implicated in inflammatory diseases, their specific genes and mechanisms...

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Bibliographic Details
Main Authors: Jinshuai Lu, Jianhao Wang, Kun Han, Yuxia Tao, Jiyi Dong, Xiaoyu Pan, Xiaolan Wen
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-03-01
Series:Frontiers in Immunology
Subjects:
sepsis
N6-methyladenosine
ferroptosis
biomarkers
single-cell RNA sequencing
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1543517/full
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https://www.frontiersin.org/articles/10.3389/fimmu.2025.1543517/full

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