InSituCor: exploring spatially correlated genes conditional on the cell type landscape

InSituCor: exploring spatially correlated genes conditional on the cell type landscape

Abstract In spatial transcriptomics data, spatially correlated genes promise to reveal high-interest phenomena like cell–cell interactions and latent variables. But in practice, most spatial correlations arise from the spatial arrangement of cell types, obscuring the more interesting relationships w...

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Bibliographic Details
Main Authors: Patrick Danaher, Dan McGuire, Lidan Wu, Michael Patrick, David Kroeppler, Haiyan Zhai, Deniz G. Olgun, Dennis Gong, Jingyi Cao, William L. Hwang, Joachim Schmid, Joseph M. Beechem
Format: Article
Language:English
Published: BMC 2025-04-01
Series:Genome Biology
Subjects:
Spatial transcriptomics
Spatial correlation
Statistical methods
Online Access:https://doi.org/10.1186/s13059-025-03554-1
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https://doi.org/10.1186/s13059-025-03554-1

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