Exploring methylation signatures for high de novo recurrence risk in hepatocellular carcinoma

Exploring methylation signatures for high de novo recurrence risk in hepatocellular carcinoma

Background/Aims Hepatocellular carcinoma (HCC) exhibits high de novo recurrence rates post-resection. Current post-surgery recurrence prediction methods are limited, emphasizing the need for reliable biomarkers to assess recurrence risk. We aimed to develop methylation-based markers for classifying...

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Main Authors: Da-Won Kim, Jin Hyun Park, Suk Kyun Hong, Min-Hyeok Jung, Ji-One Pyeon, Jin-Young Lee, Kyung-Suk Suh, Nam-Joon Yi, YoungRok Choi, Kwang-Woong Lee, Young-Joon Kim
Format: Article
Language:English
Published: Korean Association for the Study of the Liver 2025-04-01
Series:Clinical and Molecular Hepatology
Subjects:
hepatocellular carcinoma
dna methylation
biomarker
recurrence
machine learning
Online Access:http://e-cmh.org/upload/pdf/cmh-2024-0899.pdf
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http://e-cmh.org/upload/pdf/cmh-2024-0899.pdf

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