Astragaloside IV relieves passive heymann nephritis and podocyte injury by suppressing the TRAF6/NF-κb axis

Astragaloside IV relieves passive heymann nephritis and podocyte injury by suppressing the TRAF6/NF-κb axis

The pathogenesis of membranous nephropathy (MN) involves podocyte injury that is attributed to inflammatory responses induced by local immune deposits. Astragaloside IV (AS-IV) is known for its robust anti-inflammatory properties. Here, we investigated the effects of AS-IV on passive Heymann nephrit...

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Bibliographic Details
Main Authors: Yuhua Ma, Yuwen Hu, Yilin Ruan, Xiaocheng Jiang, Min Zhao, Yuxin Wang, Yanrong Ke, Manman Shi, Guoyuan Lu
Format: Article
Language:English
Published: Taylor & Francis Group 2024-12-01
Series:Renal Failure
Subjects:
Membranous nephropathy
Astragaloside IV
podocyte
T RAF6
NF-κb
Online Access:https://www.tandfonline.com/doi/10.1080/0886022X.2024.2371992
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https://www.tandfonline.com/doi/10.1080/0886022X.2024.2371992

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