Rhein restores the sensitivity of mcr-1 carrying multidrug-resistant Escherichia coli to colistin

The emergence of the colistin resistance gene mcr-1 has resulted in a significant reduction in the clinical efficacy of colistin against infections caused by multidrug-resistant Gram-negative pathogens. A cost-effective approach for restoring the efficacy of antibiotics is to formulate synergistic a...

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Bibliographic Details
Main Authors: Nannan Wang, Dan Yang, Lijuan Cao, Xinghong Zhao, Xu Song, Xun Zhou, Renyong Jia, Yuanfeng Zou, Lixia Li, Cheng Lv, Bo Jing, Zhongqiong Yin
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Microbiology
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Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2025.1586553/full
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