De Novo Variant in the RPL27 Gene in a Second Infant with Diamond-Blackfan Anemia

We describe a 10-month-old female with Diamond-Blackfan anemia (DBA) who presented with macrocytic anemia and reticulocytopenia. Whole exome sequencing revealed a de novo intronic variant in RPL27 (NM_000988.3:c.-2-1G > A p.?) previously reported in one individual with DBA. The existing literatur...

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Bibliographic Details
Main Authors: Joshua Glass, Julia Weston, Amy Feldman Lewanda, Suvankar Majumdar
Format: Article
Language:English
Published: Wiley 2024-01-01
Series:Case Reports in Hematology
Online Access:http://dx.doi.org/10.1155/2024/6626388
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