Role of interleukin-1 and tumour necrosis factor in leukocyte recruitment to acute dermal inflammation

The cytokines IL-1 and TNF-α are involved in inflammation and their production is stimulated by various agents, especially endotoxin (LPS). Here, using the human IL-1 receptor antagonist (IL-1RA) and a new monoclonal antibody (mAb 7F11) to rabbit TNF, the role of endogenous IL-l and TNF production i...

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Bibliographic Details
Main Authors: Andrew C. Issekutz, Nancy Lopes, Thomas B. Issekutz
Format: Article
Language:English
Published: Wiley 1992-01-01
Series:Mediators of Inflammation
Online Access:http://dx.doi.org/10.1155/S0962935192000528
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