Nucleophilic addition to carbonyl groups from qualitative to quantitative computational studies. A historical perspective
Nucleophilic addition to carbonyl groups is one of the most important reactions in organic synthesis. In the case of a prochiral carbonyl group, the preference for the addition of a nucleophile to one face of the ${\pi }$ system leads to unequal amounts of the two possible diastereoisomers. The mech...
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| Format: | Article |
| Language: | English |
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Académie des sciences
2024-03-01
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| Series: | Comptes Rendus. Chimie |
| Subjects: | |
| Online Access: | https://comptes-rendus.academie-sciences.fr/chimie/articles/10.5802/crchim.298/ |
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