Presentation matters: Impact of association of amphiphilic LPS with serum carrier proteins on innate immune signaling.

Presentation matters: Impact of association of amphiphilic LPS with serum carrier proteins on innate immune signaling.

Recognition of Pathogen-associated Molecular Patterns (PAMPs) by Toll-like receptors is central to innate immunity. Many bacterial PAMPs such as lipopolysaccharide (LPS) and lipoteichoic acid have amphiphilic properties. The hydrophobicity of amphiphilic PAMPs contributes to increasing entropy and c...

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Bibliographic Details
Main Authors: Loreen R Stromberg, Heather M Mendez, Jessica Z Kubicek-Sutherland, Steven W Graves, Nicolas W Hengartner, Harshini Mukundan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:https://storage.googleapis.com/plos-corpus-prod/10.1371/journal.pone.0198531/1/pone.0198531.pdf?X-Goog-Algorithm=GOOG4-RSA-SHA256&X-Goog-Credential=wombat-sa%40plos-prod.iam.gserviceaccount.com%2F20210217%2Fauto%2Fstorage%2Fgoog4_request&X-Goog-Date=20210217T193538Z&X-Goog-Expires=3600&X-Goog-SignedHeaders=host&X-Goog-Signature=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