Quantitative PET imaging and modeling of molecular blood-brain barrier permeability

Quantitative PET imaging and modeling of molecular blood-brain barrier permeability

Abstract Neuroimaging of blood-brain barrier permeability has been instrumental in identifying its broad involvement in neurological and systemic diseases. However, current methods evaluate the blood-brain barrier mainly as a structural barrier. Here we developed a non-invasive positron emission tom...

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Main Authors: Kevin J. Chung, Yasser G. Abdelhafez, Benjamin A. Spencer, Terry Jones, Quyen Tran, Lorenzo Nardo, Moon S. Chen, Souvik Sarkar, Valentina Medici, Victoria Lyo, Ramsey D. Badawi, Simon R. Cherry, Guobao Wang
Format: Article
Language:English
Published: Nature Portfolio 2025-03-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-58356-7
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https://doi.org/10.1038/s41467-025-58356-7

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