Cryoablation-induced modulation of Treg cells and the TGF-β pathway in lung adenocarcinoma: implications for increased antitumor immunity

Cryoablation-induced modulation of Treg cells and the TGF-β pathway in lung adenocarcinoma: implications for increased antitumor immunity

Background Cryoablation plays a key role in the comprehensive management of lung adenocarcinoma, characterized by its ability to activate antitumor immunity. This study aimed to explore the impact of cryoablation on the local immune microenvironment, focusing on regulatory T cells (Tregs) and the TG...

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Bibliographic Details
Main Authors: Shicheng Lin, Dianna Liu, Tianyu Liang, Yaoxue Zhuang, Xiaofan Wang, Shengmao Ma, Quanwang Li, Kaiwen Hu
Format: Article
Language:English
Published: BMC 2025-02-01
Series:BMC Medicine
Subjects:
Cryoablation
Tregs
TGF-β pathway
Single-cell sequencing
Immune responses
Online Access:https://doi.org/10.1186/s12916-025-03926-1
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https://doi.org/10.1186/s12916-025-03926-1

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