PhyloTune: An efficient method to accelerate phylogenetic updates using a pretrained DNA language model

Abstract Understanding the phylogenetic relationships among species is crucial for comprehending major evolutionary transitions. Despite the ever-growing volume of sequence data, constructing reliable phylogenetic trees effectively becomes more challenging for current analytical methods. In this stu...

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Bibliographic Details
Main Authors: Danruo Deng, Wuqin Xu, Bian Wu, Hans Peter Comes, Yu Feng, Pan Li, Jinfang Zheng, Guangyong Chen, Pheng-Ann Heng
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-61684-3
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