Assessment of the Therapeutic Potential of Enhancer of Zeste Homolog 2 Inhibition in a Murine Model of Bronchiolitis Obliterans Syndrome

Assessment of the Therapeutic Potential of Enhancer of Zeste Homolog 2 Inhibition in a Murine Model of Bronchiolitis Obliterans Syndrome

Bronchiolitis obliterans syndrome (BOS) is a chronic complication following lung transplantation that limits the long-term survival. Although the enhancer of zeste homolog 2 (EZH2) is involved in post-transplantation rejection, its involvement in BOS pathogenesis remains unclear. We aimed to investi...

Full description

Saved in:
Bibliographic Details
Main Authors: Kyoto Matsudo, Shinkichi Takamori, Tomoyoshi Takenaka, Mototsugu Shimokawa, Asato Hashinokuchi, Taichi Nagano, Fumihiko Kinoshita, Takaki Akamine, Mikihiro Kohno, Gouji Toyokawa, Tomoharu Yoshizumi
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-10-01
Series:Transplant International
Subjects:
bronchiolitis obliterans syndrome
chronic lung allograft dysfunction
3-deazaneplanocin A
enhancer of zeste homolog 2
lung transplantation
Online Access:https://www.frontierspartnerships.org/articles/10.3389/ti.2024.13227/full
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://www.frontierspartnerships.org/articles/10.3389/ti.2024.13227/full

Similar Items