Immunomarker profiling in human chronic wound swabs reveals IL-1 beta/IL-1RA and CXCL8/CXCL10 ratios as potential biomarkers for wound healing, infection status and regenerative stage

Immunomarker profiling in human chronic wound swabs reveals IL-1 beta/IL-1RA and CXCL8/CXCL10 ratios as potential biomarkers for wound healing, infection status and regenerative stage

Abstract Background Chronic wounds, such as diabetic foot ulcers, venous leg ulcers, and post-surgical wound healing disorders pose a significant challenge due to prolonged healing, risk of infection, and impaired quality of life. Persistent inflammation and impaired tissue remodeling are common in...

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Bibliographic Details
Main Authors: Julian-Dario Rembe, Waseem Garabet, Matthias Augustin, Joachim Dissemond, Wiebke Ibing, Hubert Schelzig, Ewa K. Stuermer
Format: Article
Language:English
Published: BMC 2025-04-01
Series:Journal of Translational Medicine
Subjects:
Wound healing
Tissue regeneration
Immunomarker
Wound infection
Wound swabbing
Wound micro-environment
Online Access:https://doi.org/10.1186/s12967-025-06417-2
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https://doi.org/10.1186/s12967-025-06417-2

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