Exploiting functional regions in the viral RNA genome as druggable entities

RNA-targeting compounds or small interfering RNAs (siRNAs) offer a potent means to control viral infections. An essential prerequisite for their design depends on identifying conserved and functional viral RNA structures in cells. Techniques that probe RNA structures in situ have recently been devel...

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Bibliographic Details
Main Authors: Dehua Luo, Yingge Zheng, Zhiyuan Huang, Zi Wen, Lijun Guo, Yingxiang Deng, Qingling Li, Yuqing Bai, Shozeb Haider, Dengguo Wei
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2025-07-01
Series:eLife
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Online Access:https://elifesciences.org/articles/103923
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