Large changes in detected selection signatures after a selection limit in mice bred for voluntary wheel-running behavior.

In various organisms, sequencing of selectively bred lines at apparent selection limits has demonstrated that genetic variation can remain at many loci, implying that evolution at the genetic level may continue even if the population mean phenotype remains constant. We compared selection signatures...

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Bibliographic Details
Main Authors: David A Hillis, Liran Yadgary, George M Weinstock, Fernando Pardo-Manuel de Villena, Daniel Pomp, Theodore Garland
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2024-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0306397
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