The sensor histidine kinase PhcS participates in the regulation of quorum sensing-dependent virulence genes in Ralstonia pseudosolanacearum strain OE1-1

The sensor histidine kinase PhcS participates in the regulation of quorum sensing-dependent virulence genes in Ralstonia pseudosolanacearum strain OE1-1

ABSTRACT Ralstonia pseudosolanacearum strain OE1-1 secretes methyl 3-hydroxymyristate (3-OH MAME) as a quorum-sensing (QS) signal. Strain OE1-1 senses the chemical by the sensor histidine kinase PhcS, leading to the activation of the LysR family transcriptional regulator PhcA. The activated PhcA con...

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Bibliographic Details
Main Authors: Wakana Senuma, Masayuki Tsuzuki, Chika Takemura, Yuki Terazawa, Akinori Kiba, Kouhei Ohnishi, Kenji Kai, Yasufumi Hikichi
Format: Article
Language:English
Published: American Society for Microbiology 2025-04-01
Series:Microbiology Spectrum
Subjects:
Ralstonia pseudosolanacearum
PhcK
PhcS
quorum sensing
virulence
Online Access:https://journals.asm.org/doi/10.1128/spectrum.00059-25
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https://journals.asm.org/doi/10.1128/spectrum.00059-25

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