PML Nuclear Bodies and Cellular Senescence: A Comparative Study of Healthy and Premature Aging Syndrome Donors’ Cells

PML Nuclear Bodies and Cellular Senescence: A Comparative Study of Healthy and Premature Aging Syndrome Donors’ Cells

Natural aging and age-related diseases involve the acceleration of replicative aging, or senescence. Multiple proteins are known to participate in these processes, including the promyelocytic leukemia (PML) protein, which serves as a core component of nuclear-membrane-less organelles known as PML nu...

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Bibliographic Details
Main Authors: Eugene Y. Smirnov, Sergey A. Silonov, Eva A. Shmidt, Aleksandra V. Nozdracheva, Nadezhda M. Pleskach, Mirya L. Kuranova, Anastasia A. Gavrilova, Anna E. Romanovich, Irina M. Kuznetsova, Konstantin K. Turoverov, Alexander V. Fonin
Format: Article
Language:English
Published: MDPI AG 2024-12-01
Series:Cells
Subjects:
aging
age-related diseases
senescence
cellular aging
PML nuclear bodies
LLPS
Online Access:https://www.mdpi.com/2073-4409/13/24/2075
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https://www.mdpi.com/2073-4409/13/24/2075

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