Unveiling the power of plumbagin: revitalizing exhausted T cells to combat tongue cancer

Abstract Background Tongue squamous cell carcinoma (TSCC), the most common form of oral cancer, has a poor prognosis associated with immune escape due to T cell exhaustion within the tumor microenvironment (TME). Numerous studies have demonstrated the anticancer properties of plumbagin; however, the...

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Bibliographic Details
Main Authors: Rongrong Zhang, Qingkun Jiang, Runying Guo, Ke Guo, Jiaxuan Qiu
Format: Article
Language:English
Published: BMC 2025-07-01
Series:Cancer Cell International
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Online Access:https://doi.org/10.1186/s12935-025-03892-x
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