Computational pathology assessments of cardiac stromal remodeling: Clinical correlates and prognostic implications in heart transplantation

Computational pathology assessments of cardiac stromal remodeling: Clinical correlates and prognostic implications in heart transplantation

Background: The hostile immune environment created by allotransplantation can accelerate pathologic tissue remodeling. Both overt and indolent inflammatory insults propel this remodeling, but there is a paucity of tools for monitoring the speed and severity of remodeling over time. Methods: This ret...

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Main Authors: Eliot G. Peyster, MD, MSc, Cai Yuan, PhD, Sara Arabyarmohammadi, PhD, Priti Lal, MD, Michael D. Feldman, MD, PhD, Pingfu Fu, PhD, Kenneth B. Margulies, MD, MS, Anant Madabhushi, PhD, FAIMBE, FIEEE, FNAI
Format: Article
Language:English
Published: Elsevier 2025-02-01
Series:JHLT Open
Subjects:
digital pathology
cardiac remodeling
cardiac stroma
allograft rejection
heart transplantation
Online Access:http://www.sciencedirect.com/science/article/pii/S2950133424001526
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