Translational error in mice increases with ageing in an organ-dependent manner

Abstract The accuracy of protein synthesis and its relation to ageing has been of long-standing interest. To study whether spontaneous changes in the rate of ribosomal error occur as a function of age, we first determined that stop-codon readthrough is a more sensitive read-out of mistranslation due...

Full description

Saved in:
Bibliographic Details
Main Authors: Erik C. Böttger, Harshitha Santhosh Kumar, Adrian Steiner, Emmanuel Sotirakis, Kader Thiam, Patricia Isnard Petit, Petra Seebeck, David P. Wolfer, Dimitri Shcherbakov, Rashid Akbergenov
Format: Article
Language:English
Published: Nature Portfolio 2025-02-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-57203-z
Tags: Add Tag
No Tags, Be the first to tag this record!