NKD1 enhances colon cancer progression by inhibiting the autophagic degradation of MYC

Abstract NKD1 is a known suppressor of the Wnt/β-catenin pathway. However, our previous study revealed that NKD1 could promote the proliferation and migration of colon cancer cells, enhancing colon cancer progression via unknown mechanisms. In the present study, we found that peroxisome proliferator...

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Main Authors: Wenbin Lu, Jianjun Tang, Yue Wang, Xiaoyan Gu, Hua Zhang, Yungang Liu, Ying Xiao, Qi Zhu, Jianzhong Deng, Ying Shen, Anqi Jiang, Yixin Xu, Jianhua Jin, Yongzhong Hou, Qian Liu
Format: Article
Language:English
Published: Nature Publishing Group 2025-07-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-025-07875-8
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