Causal association between gut microbiota and endometrial cancer in European and East Asian populations: a two-sample Mendelian randomization study

Causal association between gut microbiota and endometrial cancer in European and East Asian populations: a two-sample Mendelian randomization study

Abstract Background Endometrial cancer (EC) is a significant global health concern. While observational epidemiological studies suggest a potential link between gut microbiota dysbiosis and the development of EC, the direction and causality of this association remain uncertain. Methods We performed...

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Main Authors: Jiaqi Chen, Haiqing Li, Xinrui Long, Hao Tong, Xin Xin, Han Zhang, Yeyao Li, Ping Liu, Xiaolin He, Zhuoyuan Chen
Format: Article
Language:English
Published: BMC 2025-06-01
Series:BMC Women's Health
Subjects:
Gut microbiota
Endometrial cancer
Mendelian randomization
Causal relationship
Instrumental variables
Online Access:https://doi.org/10.1186/s12905-025-03789-x
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https://doi.org/10.1186/s12905-025-03789-x

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