Data mining antibody sequences for database searching in bottom-up proteomics

Mass spectrometry-based proteomics facilitates the identification and quantification of thousands of proteins but encounters challenges in measuring human antibodies due to their vast diversity. Bottom-up proteomics methods primarily rely on database searches, comparing experimental peptide values t...

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Bibliographic Details
Main Authors: Xuan-Tung Trinh, Rebecca Freitag, Konrad Krawczyk, Veit Schwämmle
Format: Article
Language:English
Published: Elsevier 2024-09-01
Series:ImmunoInformatics
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Online Access:http://www.sciencedirect.com/science/article/pii/S2667119024000120
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