RAC1 promotes the occurrence and development of tongue squamous cell carcinoma by regulating RAC1/PAK1/LIMK1 signaling pathway

RAC1 promotes the occurrence and development of tongue squamous cell carcinoma by regulating RAC1/PAK1/LIMK1 signaling pathway

Abstract Tongue squamous cell carcinoma (TSCC) remains an unsolved medical problem due to its poor local recurrence rate and prognosis. The purpose of this study was to investigate the expression characteristics of RAC-related C3 botulinum toxin substrate 1(RAC1) in TSCCS and its role in tumor invas...

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Bibliographic Details
Main Authors: Zongxuan He, Kai Song, Hongyu Han, Lin Wang, Zhenggang Chen, Wei Shang
Format: Article
Language:English
Published: Nature Portfolio 2025-03-01
Series:Scientific Reports
Subjects:
RAC1
Tongue squamous cell carcinoma
Prognosis
Metastasis
EMT
Online Access:https://doi.org/10.1038/s41598-025-92538-z
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https://doi.org/10.1038/s41598-025-92538-z

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