Colon-Targeted Mucoadhesive PLGA Microspheres Loaded with <i>Ramulus Mori</i> Alkaloids for Enhanced Water-Soluble Drug Delivery in Ulcerative Colitis Treatment

Colon-Targeted Mucoadhesive PLGA Microspheres Loaded with <i>Ramulus Mori</i> Alkaloids for Enhanced Water-Soluble Drug Delivery in Ulcerative Colitis Treatment

Ulcerative colitis (UC) is a chronic inflammation disease with severe impact on quality of life, with limited treatment options. <i>Ramulus Mori</i> alkaloids (SZ-A) from Morus alba show promise for UC treatment due to their safety and pharmacological effects, including anti-inflammation...

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Bibliographic Details
Main Authors: Mo Wang, Yu Jiang, Zhiyang Chen, Dengbao Jiang, Xuan Jiang, Jun Ye, Hongliang Wang, Yuling Liu
Format: Article
Language:English
Published: MDPI AG 2025-04-01
Series:Molecules
Subjects:
ulcerative colitis
<i>Ramulus Mori</i> alkaloids
microsphere
anti-inflammatory
PLGA
Online Access:https://www.mdpi.com/1420-3049/30/9/1878
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