Biomolecular condensates in cancer cell biology: interleukin-6-induced cytoplasmic and nuclear STAT3/PY-STAT3 condensates in hepatoma cells

Biomolecular condensates in cancer cell biology: interleukin-6-induced cytoplasmic and nuclear STAT3/PY-STAT3 condensates in hepatoma cells

We highlight previous incompletely understood cell biology data in the STAT3 signaling field with respect to interleukin-6 (IL-6)-induced activation of this transcription factor in hepatoma cells to generate cytoplasmic and nuclear STAT3 bodies. We provide a novel re-interpretation of the previous o...

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Bibliographic Details
Main Author: Pravin B. Sehgal
Format: Article
Language:English
Published: Termedia Publishing House 2019-02-01
Series:Contemporary Oncology
Subjects:
interleukin-6
cytokine-inducible biomolecular condensates
cytoplasmic STAT3 sequestering condensates
nuclear STAT3 bodies
1
6-hexanediol
liquid-like condensates
Tyr phosphorylation-driven phase transitions
tonicity-driven phase transitions
cytokine signaling
Online Access:https://www.termedia.pl/Biomolecular-condensates-in-cancer-cell-biology-interleukin-6-induced-cytoplasmic-and-nuclear-STAT3-PY-STAT3-condensates-in-hepatoma-cells,3,35863,1,1.html
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https://www.termedia.pl/Biomolecular-condensates-in-cancer-cell-biology-interleukin-6-induced-cytoplasmic-and-nuclear-STAT3-PY-STAT3-condensates-in-hepatoma-cells,3,35863,1,1.html

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