Identifying Allosteric Small-Molecule Binding Sites of Inactive NS2B-NS3 Proteases of Pathogenic <i>Flaviviridae</i>
Dengue, West Nile, Zika, Yellow fever, and Japanese encephalitis viruses persist as significant global health threats. The development of new therapeutic strategies based on inhibiting essential viral enzymes or viral–host protein interactions is problematic due to the fast mutation rate and rapid e...
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Main Authors: | Hovakim Grabski, Siranuysh Grabska, Ruben Abagyan |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2024-12-01
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Series: | Viruses |
Subjects: | |
Online Access: | https://www.mdpi.com/1999-4915/17/1/6 |
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