Improvement of carboplatin chemosensitivity in lung cancer cells by siRNA-mediated downregulation of DLGAP1-AS2 expression

Improvement of carboplatin chemosensitivity in lung cancer cells by siRNA-mediated downregulation of DLGAP1-AS2 expression

Abstract Despite being one of the primary and most effective treatments for advanced stages of lung cancer, chemotherapy drugs like carboplatin have limitations due to their adverse side effects and the development of drug resistance in lung cancer cells. However, recent studies have shown promising...

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Main Authors: Sania Ghobadi Alamdari, Reza Mohammadzadeh, Mohammad Amini, Souzan Najafi, Behzad Baradaran, Seyedeh Zahra Bahojb Mahdavi, Amirhossein Yari, Amir Ali Mokhtarzadeh
Format: Article
Language:English
Published: Nature Portfolio 2025-03-01
Series:Scientific Reports
Subjects:
Combination therapy
Lung cancer
Carboplatin
Cell migration
LncRNA-DLGAP1-AS2
Online Access:https://doi.org/10.1038/s41598-025-87649-6
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https://doi.org/10.1038/s41598-025-87649-6

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