Extensive modulation of the circulating blood proteome by hormonal contraceptive use across two population studies

Abstract Background The study of circulating blood proteins in population cohorts offers new avenues to explore lifestyle-related and genetic influences describing and shaping human health. Methods Utilizing high-throughput mass spectrometry, we quantified 148 highly abundant proteins, functioning i...

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Main Authors: Nikola Dordevic, Clemens Dierks, Essi Hantikainen, Vadim Farztdinov, Fatma Amari, Vinicius Verri Hernandes, Alessandro De Grandi, Francisco S. Domingues, Orr Shomroni, Kathrin Textoris-Taube, Vivien Bahr, Hannah Schmid, Ilja Demuth, Florian Kurth, Michael Mülleder, Peter Paul Pramstaller, Johannes Rainer, Markus Ralser
Format: Article
Language:English
Published: Nature Portfolio 2025-04-01
Series:Communications Medicine
Online Access:https://doi.org/10.1038/s43856-025-00856-0
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