Unmasking insulinoma following commencement of somatostatin analogues in malignant neuroendocrine tumours

Unmasking insulinoma following commencement of somatostatin analogues in malignant neuroendocrine tumours

Objective: Somatostatin analogues (SSA) are used in the management of patients with metastatic gastroenteropancreatic neuroendocrine tumours (GEP-NET) to control hormone secretion and tumour growth. SSA can paradoxically worsen or unmask hypoglycaemia in patients with insulinoma by inhibiting counte...

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Main Authors: Isuru Gamage, Emma Boehm, Gaurav Ghosh, Grace Kong, Michael Michael, HuiLi Wong, Oliver Piercey, Nirupa Sachithanandan
Format: Article
Language:English
Published: Bioscientifica 2025-07-01
Series:Endocrine Oncology
Subjects:
insulinoma
neuroendocrine neoplasms
somatostatin analogue
peptide receptor radionuclide therapy
radionuclide therapy
neuroendocrine tumour
hypoglycaemia
metastatic insulinoma
metastatic neuroendocrine tumour
Online Access:https://eo.bioscientifica.com/view/journals/eo/5/1/EO-25-0005.xml
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