Osteoclast-like multinucleated giant cells reinforce polycaprolactone grafts

Osteoclast-like multinucleated giant cells reinforce polycaprolactone grafts

Successful application of advanced engineered materials in osteoplasty requires a biological understanding of the recipient reaction. The immune system acts like a double-edged sword by maintaining targeted tissue and rejecting grafts. Nevertheless, even for promising graft materials such as polycap...

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Main Authors: Halldór Bjarki Einarsson, Anders Frisk Mortensen, Morten Schallburg Nielsen, Menglin Chen, Søren Roesgaard Nielsen, David Christian Evar Kraft, Jonas Jensen, Mette Bjerre, Morten Nørregaard Andersen, Jens Vinge Nygaard, Cody Eric Bünger, Thomas Vorup-Jensen
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Frontiers in Immunology
Subjects:
polycaprolactone implants
monocyte
multinucleated giant cells
integrins
dynamic mechanical analysis
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1572238/full
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https://www.frontiersin.org/articles/10.3389/fimmu.2025.1572238/full

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