Sprayable inflammasome-inhibiting lipid nanorods in a polymeric scaffold for psoriasis therapy

Abstract Localized delivery of inflammasome inhibitors in phagocytic macrophages could be promising for psoriasis treatment. The present work demonstrates the development of non-spherical lipid nanoparticles, mimicking pathogen-like shapes, consisting of an anti-inflammatory inflammasome inhibiting...

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Bibliographic Details
Main Authors: Dhanashree Surve, Adam Fish, Maharshi Debnath, Aniruddha Pinjari, Adrian Lorenzana, Sumi Piya, Shelly Peyton, Ashish Kulkarni
Format: Article
Language:English
Published: Nature Portfolio 2024-10-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-53396-x
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