A significant correlation exists between CREBBP and CEBPA gene expression in de Novo adult acute myeloid leukemia

A significant correlation exists between CREBBP and CEBPA gene expression in de Novo adult acute myeloid leukemia

Abstract CREBBP, CEBPA, and DNMT3A are tumor suppressor genes whose dysfunction has been reported in hematologic malignancies. Acute myeloid leukemia (AML) is the most common type of acute leukemia in adults. We aim to assess the expression level of CREBBP, CEBPA, and DNMT3A genes in an Egyptian coh...

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Main Authors: Magda Assem, Asmaa A. El Leithy, Naglaa M. Hassan, Ahmed A. Al-Karmalawy, Mohamed Abozaid, Rasha Mahmoud Allam, Mohamed A. M. Kamal, Marwa Amer, Gharieb S. El-Sayyad, Noha H. Ibrahim
Format: Article
Language:English
Published: Nature Portfolio 2025-04-01
Series:Scientific Reports
Subjects:
CREBBP
CEBPA
DNMT3A
RT-PCR
Acute myeloid leukemia
Online Access:https://doi.org/10.1038/s41598-025-93024-2
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https://doi.org/10.1038/s41598-025-93024-2

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